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Organic compounds that contain a carboxyl group bonded to an organic functional group; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from carboxylic acids.
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N-Hydroxyphthalimide is a blocking agent and catalyst N-Hydroxyphthalimide promotes oxidation reactions by generating PINO free radicals and activating hydrogen atom transfer processes N-Hydroxyphthalimide reduces the expression of anti-apoptotic proteins Survivin and Bcl-xL and activates caspase 9 and caspase 3 N-Hydroxyphthalimide induces Apoptosis N-Hydroxyphthalimide inhibits the phosphorylation of mTOR (Ser2448 Ser2481) and Akt (Ser473) N-Hydroxyphthalimide has anticancer effects against breast and colon cancer[1][2][3]
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Mal-Ph-CONH-PEG4-NHS ester is an ADC linker with a molecular formula of C26H31N3O11 and a molecular weight of 561.54. This product is related to the Antibody-drug Conjugate/ADC pathway.
Non-cleavable 4-unit PEG ADC linker
Utilized in the synthesis of antibody-drug conjugates (ADCs)
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